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Special Precautions for Disposal and Other Handling: For single-use only. After opening, unused product should be discarded.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.
Both the undiluted form and the infusion mixture are suitable for use as long as they remain free of haziness and precipitate.
The diluted infusion mixture (phenytoin plus normal saline) should not be refrigerated. If the undiluted parenteral phenytoin is refrigerated or frozen, a precipitate might form; this should dissolve again after the solution is allowed to stand at room temperature, in which case the product is still suitable for use. A faint yellow coloration may develop; however, this should have no effect on the potency of the solution.
Incompatibilities: Parenteral phenytoin should not be added to dextrose or dextrose-containing solutions due to the potential for precipitation.
